Alterations in chromatin accessibility during osteoblast and adipocyte differentiation in human mesenchymal stem cells

• Main Authors: Jianyun Liu (Author), Lijun Gan (Author), Baichen Ma (Author), Shan He (Author), Ping Wu (Author), Huiming Li (Author), Jianjun Xiong (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Although differential expression of genes is apparent during the adipogenic/osteogenic differentiation of marrow mesenchymal stem cells (MSCs), it is not known whether this is associated with changes in chromosomal structure. In this study, we used ATAC-sequencing technology to observe vari...