Exploiting orthology and de novo transcriptome assembly to refine target sequence information

• Asıl Yazarlar: Julia F. Söllner (Yazar), Germán Leparc (Yazar), Matthias Zwick (Yazar), Tanja Schönberger (Yazar), Tobias Hildebrandt (Yazar), Kay Nieselt (Yazar), Eric Simon (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2019-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background The ability to generate recombinant drug target proteins is important for drug discovery research as it facilitates the investigation of drug-target-interactions in vitro. To accomplish this, the target's exact protein sequence is required. Public databases, such as Ensembl,...