CRISPR/Cas9 Ablated BCL11A Unveils the Genes with Possible Role of Globin Switching

• Asıl Yazarlar: Fatemeh Movahedi Motlagh (Yazar), Hamid Reza Soleimanpour‐Lichaei (Yazar), Mehdi Shamsara (Yazar), Azadeh Etemadzadeh (Yazar), Mohammad Hossein Modarressi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Tabriz University of Medical Sciences, 2023-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Purpose: Fetal hemoglobin (HbF) upregulation is a mitigating factor in β-hemoglobinopathies therapy like β-thalassemia and sickle cell diseases. Finding molecular mechanisms and the key regulators responsible for globin switching could be helpful to develop effective ways to HbF upregulation. In our...