In Silico Prediction and Prioritization of Novel Selective Antimicrobial Drug Targets in <i>Escherichia coli</i>

• 主要な著者: Frida Svanberg Frisinger (著者), Bimal Jana (著者), Stefano Donadio (著者), Luca Guardabassi (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Novel antimicrobials interfering with pathogen-specific targets can minimize the risk of perturbations of the gut microbiota (dysbiosis) during therapy. We employed an in silico approach to identify essential proteins in <i>Escherichia coli</i> that are either absent or have low sequence...