Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

• Main Authors: Xu Wu (Author), Wei Hu (Author), Lan Lu (Author), Yueshui Zhao (Author), Yejiang Zhou (Author), Zhangang Xiao (Author), Lin Zhang (Author), Hanyu Zhang (Author), Xiaobing Li (Author), Wanping Li (Author), Shengpeng Wang (Author), Chi Hin Cho (Author), Jing Shen (Author), Mingxing Li (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor cells along with a small proportion of cancer stem cells exist in a stromal microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells and extracellular components. Recent epidemiological and clinical studies strongly support that vitamin D supplementation is assoc...