Regulation of murine copper homeostasis by members of the COMMD protein family

• Main Authors: Amika Singla (Author), Qing Chen (Author), Kohei Suzuki (Author), Jie Song (Author), Alina Fedoseienko (Author), Melinde Wijers (Author), Adam Lopez (Author), Daniel D. Billadeau (Author), Bart van de Sluis (Author), Ezra Burstein (Author)
• Format: Book
• Published: The Company of Biologists, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Copper is an essential transition metal for all eukaryotes. In mammals, intestinal copper absorption is mediated by the ATP7A copper transporter, whereas copper excretion occurs predominantly through the biliary route and is mediated by the paralog ATP7B. Both transporters have been shown to be recy...