Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport

• Egile Nagusiak: Jennifer Lee (Egilea), Jacqueline Koehler (Egilea), Bernardo Yusta (Egilea), Jasmine Bahrami (Egilea), Dianne Matthews (Egilea), Mahroukh Rafii (Egilea), Paul B. Pencharz (Egilea), Daniel J. Drucker (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2017-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Glucagon-like peptide-2 (GLP-2) is co-secreted with GLP-1 from gut endocrine cells, and both peptides act as growth factors to expand the surface area of the mucosal epithelium. Notably, GLP-2 also enhances glucose and lipid transport in enterocytes; however, its actions on control of ami...