Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport

• Main Authors: Jennifer Lee (Author), Jacqueline Koehler (Author), Bernardo Yusta (Author), Jasmine Bahrami (Author), Dianne Matthews (Author), Mahroukh Rafii (Author), Paul B. Pencharz (Author), Daniel J. Drucker (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Glucagon-like peptide-2 (GLP-2) is co-secreted with GLP-1 from gut endocrine cells, and both peptides act as growth factors to expand the surface area of the mucosal epithelium. Notably, GLP-2 also enhances glucose and lipid transport in enterocytes; however, its actions on control of ami...