Sustained Release of Co-Amorphous Matrine-Type Alkaloids and Resveratrol with Anti-COVID-19 Potential

• Päätekijät: Dandan Hu (Tekijä), Xin Chen (Tekijä), Duanxiu Li (Tekijä), Hailu Zhang (Tekijä), Yanwen Duan (Tekijä), Yong Huang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Matrine (MAR), oxymatrine (OMAR), and sophoridine (SPD) are natural alkaloids with varying biological activities; matrine was recently used for the treatment of coronavirus disease 2019 (COVID-19). However, the short half-lives and rapid elimination of these matrine-type alkaloids would lead to low...