Influence of the ionic strength on the physicochemical properties of methotrexate-loaded chitosan polyelectrolyte complexes

• Principais autores: Sandra Barbosa Neder Agostini (Autor), Victor Lima de Sousa Machado (Autor), Luciano Sindra Virtuoso (Autor), Denismar Alves Nogueira (Autor), Gislaine Ribeiro Pereira (Autor), Flávia Chiva Carvalho (Autor)
• Formato: Livro
• Publicado em: Universidade de São Paulo, 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Polyelectrolyte complexes (PECs) as drug delivery systems are widely explored since they are easily obtained by coacervation and biopolymers can be associated. However, particle distribution is a challenging critical parameter that has been infrequently focused. This work evaluated the effe...