Influence of the ionic strength on the physicochemical properties of methotrexate-loaded chitosan polyelectrolyte complexes

• Asıl Yazarlar: Sandra Barbosa Neder Agostini (Yazar), Victor Lima de Sousa Machado (Yazar), Luciano Sindra Virtuoso (Yazar), Denismar Alves Nogueira (Yazar), Gislaine Ribeiro Pereira (Yazar), Flávia Chiva Carvalho (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Universidade de São Paulo, 2023-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Polyelectrolyte complexes (PECs) as drug delivery systems are widely explored since they are easily obtained by coacervation and biopolymers can be associated. However, particle distribution is a challenging critical parameter that has been infrequently focused. This work evaluated the effe...