GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel‐Based Chemotherapy in Ovarian Cancer

• Main Authors: Amanda Canato Ferracini (Author), Leisa Lopes-Aguiar (Author), Gustavo Jacob Lourenço (Author), Adriana Yoshida (Author), Carmen Silva Passos Lima (Author), Luis Otávio Sarian (Author), Sophie Derchain (Author), Deanna L. Kroetz (Author), Priscila Gava Mazzola (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Variation in drug disposition genes might contribute to susceptibility to toxicities and interindividual differences in clinical management on chemotherapy for epithelial ovarian cancer (EOC). This study was designed to explore the association of GST and ABCB1 genetic variation with hematologic and...