Alpha-1 antitrypsin (AAT) reduces severity of Pseudomonas pneumonia in mice and inhibits epithelial barrier disruption and Pseudomonas invasion of respiratory epithelial cells

• Main Authors: Gregory ePott (Author), Scott eBeard (Author), Courtney eBryan (Author), Daniel eMerrick (Author), Leland eShapiro (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nosocomial pneumonia (NP) is the third most common hospital-acquired infection and the leading cause of death due to hospital-acquired infection in the US. During pneumonia and non-pneumonia severe illness, respiratory tract secretions become enriched with the serine protease neutrophil elastase (NE...