Improvement in the Oral Bioavailability and Efficacy of New Ezetimibe Formulations-Comparative Study of a Solid Dispersion and Different Micellar Systems

• Main Authors: Carlos Torrado-Salmerón (Author), Víctor Guarnizo-Herrero (Author), Teresa Gallego-Arranz (Author), Yvonne del Val-Sabugo (Author), Guillermo Torrado (Author), Javier Morales (Author), Santiago Torrado-Santiago (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ezetimibe (EZ) is a poorly water-soluble drug with low bioavailability. Strategies such as solid dispersions (SD) and micellar systems (MS) were developed to identify the most effective drug delivery formulations with the highest oral bioavailability, and to improve their lipid-lowering effect. The...