Fisetin Attenuated Oxidative Stress-Induced Cellular Damage in ARPE-19 Human Retinal Pigment Epithelial Cells Through Nrf2-Mediated Activation of Heme Oxygenase-1

• Main Authors: Cheol Park (Author), Jeong Sook Noh (Author), Youngmi Jung (Author), Sun-Hee Leem (Author), Jin Won Hyun (Author), Young-Chae Chang (Author), Taeg Kyu Kwon (Author), Gi-Young Kim (Author), Hyesook Lee (Author), Yung Hyun Choi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fisetin is a kind of bioactive flavonol, widely present in various fruits such as strawberries and apples, and is known to act as a potent free radical scavenger. However, the mechanism of action related to the antioxidant activity of this compound in human retinal pigment epithelial (RPE) cells is...