CD19+CD24hiCD38hi B Cell Dysfunction in Primary Biliary Cholangitis

• Main Authors: Qubo Chen (Author), Lanmin Lai (Author), Xiaoling Chi (Author), Xinyi Lu (Author), Huaxian Wu (Author), Jing Sun (Author), Weilin Wu (Author), Li Cai (Author), Xuan Zeng (Author), Chuyang Wang (Author), WeiCheng Chen (Author), Anping Peng (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD19+CD24hiCD38hi B cells are immature transitional B cells that, in normal individuals, exert suppressive effects by IL-10 production but are quantitatively altered and/or functionally impaired in individuals with various autoimmune diseases. Primary biliary cholangitis (PBC), an autoimmune disease...