Anti-lung cancer effect of paclitaxel solid lipid nanoparticles delivery system with curcumin as co-loading partner in vitro and in vivo

• Main Authors: Chao Pi (Author), Wenmei Zhao (Author), Mingtang Zeng (Author), Jiyuan Yuan (Author), Hongping Shen (Author), Ke Li (Author), Zhilian Su (Author), Zerong Liu (Author), Jie Wen (Author), Xinjie Song (Author), Robert J. Lee (Author), Yumeng Wei (Author), Ling Zhao (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Fag: article
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The main aim of this study was to improve the therapeutic potential of a paclitaxel (PTX) and curcumin (CU) combination regimen using solid lipid nanoparticles (SLNs). PTX and CU were successfully co-encapsulated at a predetermined ratio in SLNs (PC-SLNs) with high encapsulation efficiency (CU: 97.6...