Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome

• Autori principali: Junyu Zhai (Autore), Shang Li (Autore), Min Hu (Autore), Fangfang Di (Autore), Jiansheng Liu (Autore), Yanzhi Du (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2020-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background The interface between environmental risk factors and genetic factors could contribute to the pathogenesis of hyperandrogenism and insulin resistance in polycystic ovary syndrome (PCOS); however, the underlying complex mechanism remains to be elucidated. Methods We used dehydroepi...