Relaxant Action of Diclofenac Sodium on Mouse Airway Smooth Muscle

• Main Authors: Chunfa Chen (Author), Yongle Yang (Author), Meng-Fei Yu (Author), Shunbo Shi (Author), Shuhui Han (Author), Qing-hua Liu (Author), Congli Cai (Author), Jinhua Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diclofenac sodium (DCF) is a nonsteroidal anti-inflammatory drug (NSAID) and is widely used as an analgesic and anti-inflammatory agent. Herein, we found that DCF could relax high K+ (80 mM K+)-/ACh-precontracted tracheal rings (TRs) in mice. This study aimed to elucidate the underlying mechanisms o...