Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling

• Main Authors: Andrea Catte (Author), Venkata K. Ramaswamy (Author), Attilio Vittorio Vargiu (Author), Giuliano Malloci (Author), Andrea Bosin (Author), Paolo Ruggerone (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The secondary transporters of the resistance-nodulation-cell division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria like Pseudomonas aeruginosa. Among these RND transporters, MexB, MexF, and MexY, with partly overlapping specificities, have been implicated in pathogenicity...