Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

Temocillin is active against Gram-negative bacteria, including many extended-spectrum β-lactamase (ESBL)-producing Enterobacterales. We studied its pharmacokinetics in plasma and ascitic fluid after intravenous administration of a loading dose of 2 g over 30 min, followed by continuous infusion of 6...

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Main Authors: Perrin Ngougni Pokem (Author), Xavier Wittebole (Author), Christine Collienne (Author), Hector Rodriguez-Villalobos (Author), Paul M. Tulkens (Author), Laure Elens (Author), Françoise Van Bambeke (Author), Pierre-François Laterre (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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