Persistent follicular granulosa cell senescence and apoptosis induced by methotrexate leading to oocyte dysfunction and aberrant embryo development

• मुख्य लेखकों: Jingbo Fu (लेखक), Yang Liu (लेखक), Chen Wang (लेखक), Hongxia Zhang (लेखक), Bin Yu (लेखक), Ye Wang (लेखक), Haiying Zhu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Evidence from clinical cases indicates an association between the low success rate of in vitro fertilization (IVF) and ovarian injury due to previous methotrexate (MTX) administration. Therefore, it is necessary to develop and propose reasonable clinical drug guidelines to improve the quali...