New Quinoline-Urea-Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling

New Quinoline-Urea-Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling

A series of 25 new benzothiazole-urea-quinoline hybrid compounds were synthesized successfully via a three-step synthetic sequence involving an amidation coupling reaction as a critical step. The structures of the synthesized compounds were confirmed by routine spectroscopic tools (<sup>1</...

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Main Authors: Rashmika Moodley (Author), Chakes Mashaba (Author), Goitsemodimo H. Rakodi (Author), Nomagugu B. Ncube (Author), Mabuatsela V. Maphoru (Author), Mohammed O. Balogun (Author), Audrey Jordan (Author), Digby F. Warner (Author), Rene Khan (Author), Matshawandile Tukulula (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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