A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases

• Main Authors: Hyo-jeong Ryu (Author), Won-ho Kang (Author), Taeheon Kim (Author), Jae Kyoung Kim (Author), Kwang-Hee Shin (Author), Jung-woo Chae (Author), Hwi-yeol Yun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacokinetic (PK) modeling is a useful method for investigating drug absorption, distribution, metabolism, and excretion. The most commonly used mathematical models in PK modeling are the compartment model and physiologically based pharmacokinetic (PBPK) model. Although the theoretical characteri...