Magnolol Inhibits High Fructose-Induced Podocyte Inflammation via Downregulation of TKFC/Sp1/HDAC4/Notch1 Activation

• Main Authors: Ziang Zhou (Author), Yumeng Wang (Author), Yu Xing (Author), Shuman Pan (Author), Wanru Wang (Author), Jie Yang (Author), Wenyuan Wu (Author), Jie Zhou (Author), Luyi Huang (Author), Qiongdan Liang (Author), Dongmei Zhang (Author), Lingdong Kong (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: High fructose has been implicated as an important trigger of kidney inflammation in patients and experimental models. Magnolol, isolated from <i>Magnolia officinalis</i>, has an anti-inflammatory effect, but its protective role in podocytes remains underexplored. T...