Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling

• Main Authors: Qian Huang (Author), Rui Xiao (Author), Jing Lu (Author), Yao Zhang (Author), Liang Xu (Author), Jie Gao (Author), Jing Sun (Author), Haiping Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Peritoneal fibrosis (PF) is an intractable complication in patients on long-term peritoneal dialysis (PD). Transforming growth factor-β (TGF-β) is a key pro-fibrogenic factor involved in PD-associated PF, and endoglin, as a coreceptor for TGF-β, plays a role in balancing the TGF-β signal...