An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification

• Main Authors: Shan Lu (Author), Ziqi Meng (Author), Yingying Tan (Author), Chao Wu (Author), Zhihong Huang (Author), Jiaqi Huang (Author), Changgeng Fu (Author), Antony Stalin (Author), Siyu Guo (Author), Xinkui Liu (Author), Leiming You (Author), Xiaojiaoyang Li (Author), Jingyuan Zhang (Author), Wei Zhou (Author), Xiaomeng Zhang (Author), Miaomiao Wang (Author), Jiarui Wu (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Compound Kushen Injection (CKI) is a Chinese patent drug that exerts curative effects in the clinical treatment of hepatocellular carcinoma (HCC). This study aimed to explore the targets and potential pharmacological mechanisms of CKI in the treatment of HCC. Methods In this stud...