LXR deficiency confers increased protection against visceral Leishmania infection in mice.
The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation. LXRs also affect antimicrobial responses and have anti-inflammatory effects in macrophages. As mice lacking...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2010-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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