Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives

• Main Authors: Ivana Šagud (Author), Nikolina Maček Hrvat (Author), Ana Grgičević (Author), Tena Čadež (Author), Josipa Hodak (Author), Milena Dragojević (Author), Kornelija Lasić (Author), Zrinka Kovarik (Author), Irena Škorić (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are primary targets in attenuating the symptoms of neurodegenerative diseases. Their inhibition results in elevated concentrations of the neurotransmitter acetylcholine which supports communication among nerve cells. It was pre...