Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation

• المؤلفون الرئيسيون: Yoshikazu Nakaoka (مؤلف), Issei Komuro (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2013-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The docking proteins of the Grb2-associated binder (Gab) family have emerged as crucial signaling compartments in metazoans. In mammals, the Gab proteins, consisting of Gab1, Gab2, and Gab3, are involved in the amplification and integration of signal transduction evoked by a variety of extracellular...