Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice

• Asıl Yazarlar: Lei Li (Yazar), Daisuke Nakano (Yazar), Anqi Zhang (Yazar), Wararat Kittikulsuth (Yazar), Norihiko Morisawa (Yazar), Hiroyuki Ohsaki (Yazar), Norio Suzuki (Yazar), Masayuki Yamamoto (Yazar), Akira Nishiyama (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2020-12-01T00:00:00Z.
• Konular: article
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The kidneys are the major organs for erythropoietin (EPO) production in adults, and thus, kidney damage results in reduced EPO levels and anemia. Inhibitors of Hypoxia-inducible factor-prolyl hydroxylase domain-containing protein (HIF-PHD) are awaited as new therapeutic options for renal anemia. It...