Preparation of controlled porosity osmotic pump tablets for salvianolic acid and optimization of the formulation using an artificial neural network method

• Κύριοι συγγραφείς: Wen-Jin Xu (Συγγραφέας), Ning Li (Συγγραφέας), Chong-kai Gao (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2011-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

In this paper controlled porosity osmotic pump tablets (CPOPT) for salvianolic acid (SA) were prepared and optimized with experimental design methods including an artificial neutral network (ANN) method. Three causal factors, i.e., drug, osmotic pressure promoting agent rate, PEG400 content in coati...