Do Ophthalmic Solutions of Amphotericin B Solubilised in 2-Hydroxypropyl-γ-Cyclodextrins Possess an Extended Physicochemical Stability?

• Main Authors: Philip Chennell (Author), Mouloud Yessaad (Author), Florence Abd El Kader (Author), Mireille Jouannet (Author), Mathieu Wasiak (Author), Yassine Bouattour (Author), Valérie Sautou (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fungal keratitis is a sight-threatening disease for which amphotericin B eye drops is one of the front-line treatments. Unfortunately, there are currently no commercial forms available, and there is little data concerning the long-term stability of compounded formulations based on intravenous dosage...