HIV Productively Infects Highly Differentiated and Exhausted CD4+ T Cells During AIDS

• Main Authors: Clayton Faua (Author), Axel Ursenbach (Author), Anne Fuchs (Author), Stéphanie Caspar (Author), Frédéric Jegou (Author), Yvon Ruch (Author), Baptiste Hoellinger (Author), Elodie Laugel (Author), Aurélie Velay (Author), David Rey (Author), Samira Fafi-Kremer (Author), Pierre Gantner (Author)
• Format: Book
• Published: Case Western Reserve University, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Throughout HIV infection, productively infected cells generate billions of viral particles and are thus responsible for body-wide HIV dissemination, but their phenotype during AIDS is unknown. As AIDS is associated with immunological changes, analyzing the phenotype of productively infec...