Kv1.5 Open Channel Block by the Antiarrhythmic Drug Disopyramide: Molecular Determinants of Block

• Główni autorzy: Iván A. Aréchiga (Autor), Gabriel F. Barrio-Echavarria (Autor), Aldo A. Rodríguez-Menchaca (Autor), Eloy G. Moreno-Galindo (Autor), Niels Decher (Autor), Martin Tristani-Firouzi (Autor), José A. Sánchez-Chapula (Autor), Ricardo A. Navarro-Polanco (Autor)
• Format: Książka
• Wydane: Elsevier, 2008-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Kv1.5 is considered to be a potential molecular target for treatment of atrial fibrillation or flutter. Disopyramide is widely used in the treatment of atrial flutter and/or atrial fibrillation. The present study was undertaken to characterize the effects of disopyramide on currents mediated by Kv1....