The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer's Disease Patients and Its Consequence to Oxidative Stress Biomarkers

• Main Authors: Martin Valis (Author), David Herman (Author), Nela Vanova (Author), Jiri Masopust (Author), Oldrich Vysata (Author), Jakub Hort (Author), Zbysek Pavelek (Author), Blanka Klimova (Author), Kamil Kuca (Author), Jan Misik (Author), Jana Zdarova Karasova (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Memantine is a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist utilized as a palliative cure for Alzheimer's disease. This is the second study examining the memantine concentrations in cerebrospinal fluid. The previously published study enrolled six patients, and three of them we...