Effects of sesamin on primary human synovial fibroblasts and SW982 cell line induced by tumor necrosis factor-alpha as a synovitis-like model

• Main Authors: Manatsanan Khansai (Author), Thanyaluck Phitak (Author), Jeerawan Klangjorhor (Author), Sasimol Udomrak (Author), Kanda Fanhchaksai (Author), Peraphan Pothacharoen (Author), Prachya Kongtawelert (Author)
• Format: Book
• Published: BMC, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic synovitis, cartilage degradation and bone deformities. Synovitis is the term for inflammation of the synovial membrane, an early stage of RA. The pathogenesis of the disease occurs through cytokine induction....