CD8+ T cells are preferentially activated during primary low dose leishmania major infection but are completely dispensable during secondary anti-Leishmania immunity.

• Asıl Yazarlar: Ifeoma B Okwor (Yazar), Ping Jia (Yazar), Zhirong Mou (Yazar), Chukwunonso Onyilagha (Yazar), Jude E Uzonna (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We previously showed that CD8+ T cells are required for optimal primary immunity to low dose Leishmania major infection. However, it is not known whether immunity induced by low dose infection is durable and whether CD8+ T cells contribute to secondary immunity following recovery from low dose infec...