In Vitro and In Vivo Synergism of Fosfomycin in Combination with Meropenem or Polymyxin B against KPC-2-Producing <i>Klebsiella pneumoniae</i> Clinical Isolates

• Main Authors: Aghata Cardoso da Silva Ribeiro (Author), Yohanna Carvalho dos Santos Aoun Chikhani (Author), Tiago Barcelos Valiatti (Author), André Valêncio (Author), Mariana Neri Lucas Kurihara (Author), Fernanda Fernandes Santos (Author), Luciene Andrade da Rocha Minarini (Author), Ana Cristina Gales (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fosfomycin disodium is a potential therapeutic option to manage difficult-to-treat infections, especially when combined with other antimicrobials. In this study, we evaluated the activity of fosfomycin in combination with meropenem or polymyxin B against contemporaneous KPC-2-producing <i>K. p...