Can a propensity score matching method be applied to assessing efficacy from single‐arm proof‐of‐concept trials in oncology?

• Main Authors: Shu‐Wen Teng (Author), Yu‐Cheng Su (Author), Ravikumar Pallantla (Author), Madhav Channavazzala (Author), Rukmini Kumar (Author), Yucheng Sheng (Author), Hao Wang (Author), Crystal Wang (Author), Archie Tse (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract As a result of the escalating number of new cancer treatments being developed and competition among pharmaceutical companies, decisions regarding how to proceed with phase III trials are frequently based on findings from either single‐arm phase I expansion cohorts or phase II studies that c...