A Quantitative Pharmacology Model of Exosome-Mediated Drug Efflux and Perturbation-Induced Synergy
Exosomes, naturally occurring vesicles secreted by cells, are undergoing development as drug carriers. We used experimental and computational studies to investigate the kinetics of intracellular exosome processing and exosome-mediated drug efflux and the effects of exosome inhibition. The experiment...
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Main Authors: | Jin Wang (Author), Bertrand Z. Yeung (Author), M. Guillaume Wientjes (Author), Minjian Cui (Author), Cody J. Peer (Author), Ze Lu (Author), William D. Figg (Author), Sukyung Woo (Author), Jessie L.-S. Au (Author) |
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Format: | Book |
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MDPI AG,
2021-06-01T00:00:00Z.
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