Eosinophil granule proteins ECP and EPX as markers for a potential early-stage inflammatory lesion in female genital schistosomiasis (FGS).

• Main Authors: Charles Emile Ramarokoto (Author), Anna Overgaard Kildemoes (Author), Bodo Sahondra Randrianasolo (Author), Pascaline Ravoniarimbinina (Author), Vololomboahangy Elisabeth Ravaoalimalala (Author), Peter Leutscher (Author), Eyrun Floerecke Kjetland (Author), Birgitte Jyding Vennervald (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Genital granulomas induced by Schistosoma haematobium eggs can manifest as different lesion types visible by colposcopy; rubbery papules (RP), homogenous sandy patches (HSP) and grainy sandy patches (GSP). Pronounced tissue eosinophilia is a candidate marker for active S. haematobium pathology, as v...