Recent advances of antibody drug conjugates for clinical applications

• Үндсэн зохиолчид: Pengxuan Zhao (Зохиогч), Yuebao Zhang (Зохиогч), Wenqing Li (Зохиогч), Christopher Jeanty (Зохиогч), Guangya Xiang (Зохиогч), Yizhou Dong (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2020-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Antibody drug conjugates (ADCs) normally compose of a humanized antibody and small molecular drug via a chemical linker. After decades of preclinical and clinical studies, a series of ADCs have been widely used for treating specific tumor types in the clinic such as brentuximab vedotin (Adcetris®) f...