Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis

• Main Authors: Amir Mohamed Abdelhamid (Author), Mahmoud E. Youssef (Author), Simona Cavalu (Author), Gomaa Mostafa-Hedeab (Author), Amal Youssef (Author), Sara T. Elazab (Author), Samar Ibrahim (Author), Shady Allam (Author), Rehab Mohamed Elgharabawy (Author), Eman El-Ahwany (Author), Noha A. Amin (Author), Ahmed Shata (Author), Osama A. Mohammed (Author), Mahmoud Said Ibrahim Abdeldaiem (Author), Ahmed Alhowail (Author), Gaber El-Saber Batiha (Author), Engy A. El-Mahmoudy (Author), Maram Attia (Author), Alaa Allam (Author), Mona Y. Zaater (Author), Mona M. Osman (Author), Manar Nader (Author), Aya Taha (Author), Nada Abul Makarem (Author), Sameh Saber (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ulcerative colitis (UC), an inflammatory bowel disease, is a chronic condition of a multifaceted pathophysiology. The incidence of UC is increasing internationally. The current therapies for UC lack relative effectiveness and are associated with adverse effects. Therefore, novel therapeutic options...