Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root extract through NLRP3 inflammasome pathway inhibition

• Main Authors: Punnida Arjsri (Author), Kamonwan Srisawad (Author), Warathit Semmarath (Author), Sonthaya Umsumarng (Author), Lapamas Rueankham (Author), Aroonchai Saiai (Author), Methee Rungrojsakul (Author), Trinnakorn Katekunlaphan (Author), Songyot Anuchapreeda (Author), Pornngarm Dejkriengkraikul (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Non-small cell lung cancer (NSCLC) is recognized for its aggressive nature and propensity for high rates of metastasis. The NLRP3 inflammasome pathway plays a vital role in the progression of NSCLC. This study aimed to investigate the effects of S. exigua extract and its active compounds...