Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes

• Main Authors: Laura Marquez-Exposito (Author), Lucia Tejedor-Santamaria (Author), Laura Santos-Sanchez (Author), Floris A. Valentijn (Author), Elena Cantero-Navarro (Author), Sandra Rayego-Mateos (Author), Raul R. Rodrigues-Diez (Author), Antonio Tejera-Muñoz (Author), Vanessa Marchant (Author), Ana B. Sanz (Author), Alberto Ortiz (Author), Roel Goldschmeding (Author), Marta Ruiz-Ortega (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute kidney injury (AKI) is more frequent in elderly patients. Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle arrest) have been linked to cellular senescence, a process implicated in regeneration failure...