The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

• Main Authors: Kieran McCafferty (Author), Suzanne Forbes (Author), Christoph Thiemermann (Author), Muhammad M. Yaqoob (Author)
• Formato: Livro
• Publicado em: The Company of Biologists, 2014-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of blood supply to the affected area causes significant tissue damage. This is known as ischemia-reperfusion injury (IRI) and is a central pathological mechanism contributing to many common disease states...