De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry

• Main Authors: Verena M. Prade (Author), Thomas Kunzke (Author), Annette Feuchtinger (Author), Maria Rohm (Author), Birgit Luber (Author), Florian Lordick (Author), Achim Buck (Author), Axel Walch (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Imaging mass spectrometry enables in situ label-free detection of thousands of metabolites from intact tissue samples. However, automated steps for multi-omics analyses and interpretation of histological images have not yet been implemented in mass spectrometry data analysis workflows. T...