Cartilage‐targeting ultrasmall lipid‐polymer hybrid nanoparticles for the prevention of cartilage degradation

• Main Authors: Xiangzhao Ai (Author), Yaou Duan (Author), Qiangzhe Zhang (Author), Derrick Sun (Author), Ronnie H. Fang (Author), Ru Liu‐Bryan (Author), Weiwei Gao (Author), Liangfang Zhang (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Current drug delivery approaches for the treatment of cartilage disorders such as osteoarthritis (OA) remain inadequate to achieve sufficient drug penetration and retention in the dense cartilage matrix. Herein, we synthesize sub‐30 nm lipid‐polymer hybrid nanoparticles functionalized with...