Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury

• Main Authors: Wen-zhao Liu (Author), Zhan-jun Ma (Author), Ji-he Kang (Author), Ai-xin Lin (Author), Zhao-heng Wang (Author), Hai-wei Chen (Author), Xu-dong Guo (Author), Xue-gang He (Author), Xue-wen Kang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spinal cord injury (SCI) is a highly disabling disorder for which few effective treatments are available. Grape seed proanthocyanidins (GSPs) are polyphenolic compounds with various biological activities. In our preliminary experiment, GSP promoted functional recovery in rats with SCI, but the mecha...