9-N-n-alkyl Berberine Derivatives: Hypoglycemic Activity Evaluation

9-N-n-alkyl Berberine Derivatives: Hypoglycemic Activity Evaluation

Several novel 9-N-n-alkyl derivatives of berberine (C5, C7, C10, C12) were synthesized. They were analyzed in vitro and in vivo for their hypoglycemic activity. In vitro studies showed that the derivatives with shorter alkyl substitutes at concentrations ranging from 2.5 to 10 μM were able to stimul...

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Main Authors: Mikhail V. Khvostov (Author), Elizaveta D. Gladkova (Author), Sergey A. Borisov (Author), Marina S. Fedotova (Author), Nataliya A. Zhukova (Author), Mariya K. Marenina (Author), Yulia V. Meshkova (Author), Nicolae Valutsa (Author), Olga A. Luzina (Author), Tatiana G. Tolstikova (Author), Nariman F. Salakhutdinov (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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