Denervation does not induce muscle atrophy through oxidative stress

• Main Authors: Eva Pigna (Author), Emanuela Greco (Author), Giulio Morozzi (Author), Silvia Grottelli (Author), Alessio Rotini (Author), Alba Minelli (Author), Stefania Fulle (Author), Sergio Adamo (Author), Rosa Mancinelli (Author), Ilaria Bellezza (Author), Viviana Moresi (Author)
• Format: Book
• Published: PAGEPress Publications, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness. Furthermore, denervation induces oxidative stress in skeletal muscle, which is thought to contribute to the induction of skeletal muscle a...